The Dell OptiPlex 7060 SFF supports M.2 NVMe plus two 2.5-inch drives

One M.2 2280 slot for NVMe or SATA SSDs plus two 2.5-inch SATA drive bays with two additional SATA ports on the motherboard. That’s enough for a fast NVMe boot drive and a pair of cheap SSDs in RAID if you need redundancy.